The Role of Vitamin D and Vitamin D Receptor in Immunity to Leishmania major Infection
Vitamin D signaling modulates a variety of immune responses.Here, we assessed the role of vitamin D in immunity to experimental leishmaniasis infection in vitamin D receptor-deficient mice (VDRKO).We observed that VDRKO mice on a genetically resistant background have decreased Leishmania major-induced lesion development compared to wild-type (WT) p